热性惊厥复发危险因素与预后分析

Prognosis and risk factors for seizure recurrence in children with febrile seizures

目的 研究热性惊厥患儿的复发危险因素及预后情况。方法 结合 98例热性惊厥患儿的临床及脑电图资料 ,研究其复发、转为癫疒间和出现智力障碍及行为异常的情况。结果 复发共 5 2例 (5 3.0 % ) ,复发危险因素与惊厥家族史、初次发作体温 <38 5℃、初次发作年龄 <1岁及复杂型热性惊厥有关 (P <0 .0 1) ;热性惊厥转为癫疒间共 2 0例 (2 0 .4% ) ,转为癫疒间的危险因素与复杂型热性惊厥、初次发作年龄 <1岁、热性惊厥反复发作有关 (P<0 .0 1) ;发生智力障碍及行为异常 2例 (2 .0 % ) ,说明热性惊厥患儿绝大部分预后较好 ,智力低下及行为障碍发生率低。结论 对有复发危险因素及转为癫疒间危险因素的患儿 ,应密切随访 ,采取适当的干预措施。

Objective\ To investigate the prognosis and risk factors for seizure recurrence in children with febrile seizures(FC).Methods\ With the data of clinic and electro-encephalogram,the recurrence,the epilepsy transition,the mental retardation and behavior handicap were observed in this study.Results\ Recurrence was found in 52 cases(53 0%).And the risk factors for recurrence were:the family history of convulsion,the temperature of the first seizure,the age of onset and complicated types of FC(P<0.01).20(20 4)cases converted to epilepsy,and the risk factors of which were:complicated FC,the age of onset and the recurrence of FC(P<0 01)Most of the patients had a optimistic prognosis,while few of them turned out to be mental retardaiton and behavior handicaps(2 04%).Conclusion\ Proper intervention should be adapted in managing the patients with risk factors for recurrence.