醉鱼草化学成分的研究

Studies on chemical constituents of Buddleja lindleyana

目的 研究醉鱼草的化学成分。方法 利用硅胶色谱柱层析进行分离纯化 ,通过理化方法及光谱分析鉴定其化学结构。结果 从其全草的乙醇提取物中分得 10个化合物 ,分别鉴定为α-菠甾醇 ( )、豆甾醇 ( )、β-谷甾醇( )、熊果酸 ( )、齐墩果酸 ( )、二萜类化合物 phenanthrene( )、二十四烷酸 - α-单甘油酯 ( )、二十九烷 ( )、蒙花苷 ( )和 6 - O-香草酰筋骨草苷 ( )。结论 这些化合物均为首次从该植物中分得。

Object To study the chemical constituents of Buddleja lindleyana Fort Methods The constituents were isolated and purified by various chromatographic methods and structurally identifed by physico chemical properties and spectral analysis Results 10 compounds were obtained as α spinasterol (Ⅰ), stigmasterol (Ⅱ), β sitosterol (Ⅲ), ursolic acid (Ⅳ), oleanolic acid (Ⅴ),phenanthrene (Ⅵ), glycerol mono tetracosanoate (Ⅶ), nonacosane (Ⅷ), acaciin (Ⅸ) and 6 O vanilloyl ajugol (Ⅹ) Conclusion All these compounds were obtained from this plant for the first time