黄精和生姜抗皮肤癣菌活性研究

Study on antidermatophyte activity of Polygonatum sibiricumredoute and Zingiber officinale Rosc

目的 :观察黄精和生姜提取物抗真菌效果。方法 :采用试管内药基法对其提取物进行抗真菌实验研究。结果 :生姜提取物对常见皮肤癣菌有明显抑菌和杀菌作用 ,最低抑菌浓度 (MIC)为0 .0 62 5 %～ 0 .12 5 % ,最低杀菌浓度 (MFC)为 0 .12 5 %～ 0 .2 5 0 % ;黄精提取物的 MIC为 2 %～ 8% ,MFC为 4 %～ 8%。结论 :生姜提取物的抑菌和杀菌活性极为显著 。

Objective:We observed the antifungal effect of extraction from Polygonatum sibiricum Redoute and Zingiber officinale Rosc.Methods:The medicine-based method was used to do the experimental study on antifungalities of the extraction.Results:The extraction of Zingiber officinale Rosc had evidently fungistatic and fungicidal effect on common dermatophyte.Its MIC was 0.062 5%~0.125%,and MFC was 0.125%~ 0.25% .The MIC of extraction from Polygonatum sibiricum Redoute was 2%~8%,and MFC was 4%~8%. Conclusion :The fungistaticity and fungicidality of extraction from Zingiber officinale Rosc was significant and the fungistaticity of extration from Polygonatum sibiricum Redoute was low.