三峡库区重庆段移民区肾综合征出血热的血清流行病学调查

Seroepidemiologic study on hemorrhagic fever with renal syndrome virus in the migration areas of the Three-Gorges reservoir Chongqing region, Yangtze River

目的 了解三峡库区重庆段移民区移民人群肾综合征出血热 (HFRS)的隐性感染和免疫水平状况。方法 现场流行病学调查和血清流行病学研究。采用间接免疫荧光检测技术检测移民人群血清HFRSV IgG抗体。结果 在 5个移民区中 ,3个为HFRSV IgG抗体阳性 ,即涪陵区白涛镇、奉节县万胜乡、巫山县大昌镇 (既属搬迁区又属安置区 ) ,但滴度不高 ,抗体阳性率分别为 0 .9%、3.3%和 3.5 % ,另外 2个为移民安置区 ,其HFRSV IgG抗体为阴性。 结论 5个移民区移民人群隐性感染率低 ,免疫水平普遍低下 。

Objective To ascertain both the immune level and latent infection status among the migrants from the Three Gorge Reservoir, Chongqing Region. Methods Epidemiological survey and seroepidemiologic study were performed on the spots. Sera HFRSV IgG antibody of migrations was detected with the indirect immunofluorescent assay technique(IIFAT). Results Three in 5 migration areas were seral HFRSV antibody positive, ie Baitao Town of Fuling Section, Wansheng Village of Fengjie County and Dachang Town of Wushan County, which not only will be evacuated, but also be taken for relocation. However the antibody titer was not high, with positive rates of HFRSV IgG Ab 0.9 %, 3.3 % and 3.5 % respectively. The other two areas attributed to relocation, HFRSV IgG antibody were negative. Conclusions This article confirmed that covert infection rate of HFRS in 5 migration areas was not high. The immune level remained low. Hence, it is very necessary to enhance the immunity of the immigrants.