小剂量降纤酶溶栓治疗不稳定型心绞痛的临床观察

Observation of the thrombolytic therapeutic effect of low-does defibrase on patients with unstable angina pectoric

目的 :观察小剂量降纤酶溶栓疗法对不稳定型心绞痛 (UAP)的临床疗效。方法 :随机将36例UAP分为A、B两组。A组 ( 19例 )常规抗心肌缺血治疗加小剂量降纤酶溶栓疗法 ;B组 ( 17例 )常规抗心肌缺血治疗。结果 :A组 72h内临床疗效显效率 66.67%明显高丁B组 2 .5% (P <0 .0 2 5) ;A组72h内急性心肌梗塞 (AMl)发生率 5.56%明显低于B组 37.50 % (P <0 .0 2 5) ;随访一年间A组心脏猝死及AMI例数也明显低于B组。结论 :该疗法高效、安全、能改善UAP患者近期预后。

Objective: To observe the thrombolytic therapeutic effect of low-dose of defibraseon patients with unstable angina pectoric(UAP). Methods: In the article,36 patients with UAPwere randomly divided into two groups. The therapeutic group (A) and the control group (B), the A group (19case) was treated with low -dose defibrase,the control group (17case) was treated with the regular cure of anti-myocardiaiskemia. Results: The total effective rate of A group was superior to that of the control group (p<0.025) The rate of acute myocardial infarction (AMI) was obviously lower than the group B.(P<0.025) during 72hours,the same as the resulte after one year.Conclusions: The thrombolytic therapeutic effect of low-dose of defibrase on patients with unstable angina pectoric(UAP) is effective、 safety、and can improve the prognocis of the patients.