有机合成中的C＝C键形成新方法—原子经济的金属复分解闭环反应

New Method for Forming C =C Bonds in Organic Synthesis-Atom Economic Ring-Closing Metathesis Reactions

综述了金属复分解闭环反应最新进展.金属复分解闭环反应已成为有机合成中的非常重要的方法,广泛应用于碳环、杂环化合物及天然产物的合成.原子经济的、绿色化学的优点展示出更加诱人的前景.

Recent important progress in ring-closing metathesis of olefin is reviewed. The ring-closing metathesis recently emerges as a powerful method for the synthesis of a variety of ring systems including carbo-, and heterocycles, and has found extensive applications in the synthesis of natural products. These reactions are atom economic and meet the requirements of green chemistry.