叔胺类环钯化合物在催化Heck反应中的应用

Cyclopalladated Complexes of Tertiary Arylamines as Highly Efficient Catalysts for the Heck Reaction

首次报道了叔胺类环钯化合物1～4在催化Heck反应中的应用.实验表明该类化合物能高效地催化Heck反应;其中催化剂4的TON值(产品摩尔数与钯摩尔数的比值)和TOF值(产品摩尔数与钯摩尔数以及反应时间的比值)分别高达9.6×106和8.7×105.这是迄今为止催化Heck反应的最好结果.

Cyclopalladated complexes of tertiary arylamines 1 similar to 4 are reported for the first time with as highly efficient catalysts for the Heck reactions turnover numbers being up to 9.6 x 10(6)(mol product per mol Pd) and turnover frequencies up to 8.7 x 10(5)(mol product per mol Pd per h). This is the highest catalytic activity of all Heck reactions reported to date.