用正交试验法对宣肺祛痰口服液中盐酸麻黄碱提取工艺的研究

Studies on Extracting Techniques of Xuanfei Qutan Oral Liquid by Orthogonal Design

采用正交设计法,以提取干膏量和盐酸麻黄碱含量为考察指标,对宣肺祛痰口服液的加水量、水煮时间、提取次数三因素进行优选研究.确定了合理可行的工艺条件,即加水量为25倍量(10、8、7)、煎煮三次、每次1.5h.含量测定方法为薄层扫描法.

The optimized extracting condition of Xuanfei Qutan Oral Liquid were investigated by determining the dried extract and the content of ephedrine chloride with orthogonal design method.Three factors,water volume,decocting time and extracting times,were considered to effect the extracting efficiency of active component.The reasonable extracting conditions were to decoct for three times with water for 1\^5 hour each times,and the total water volume were 25 times corresponding to the herbal weight.The quantitative method of ephedrine chloride was used by TLC-scanning method.