TRUS13点前列腺穿刺活检术诊断前列腺癌

TRUS 13 CORES PROSTATE BIOPSY DIAGNOSING PROSTATE CARCINOMA

目的 :评价经直肠超声引导 (TRUS) 13点前列腺系统穿刺活检术诊断前列腺癌的临床价值。方法 :直肠指诊阳性和 /或PSA >4ng/ml的 5 1例患者行TRUS13点前列腺穿刺活术。参照Eskew6点法 ,同时增加前列腺中间沟 3点及前列腺两侧沟各 2点 ,总计 13点。将增加的 7点与标准的 6点病理活检比较。并对 13点活检的并发症进行讨论。结果 :5 1例中有 2 0例确诊为前列腺癌 (2 0 / 5 1) ,占 39%。 2 0例前列腺癌患者若仅采用 6点法活检 ,将有例 5患者漏诊 ,占 2 5 %。所有接受TRUS13点前列腺穿刺活检术的患者无 1例出现严重的并发症。结论 :TRUS13点前列腺穿活检术可明显提高前列腺癌的临床检出率 ,是一种安全、有效的前列腺穿刺活检术式 ,值得在临床推广应用。

Objective:To evaluate the clinial value of transrectal ultrasound guided (TRUS) 13 cores prostate biopsy.Methods:A total of 51 patients referred for abnormal digital rectal examination and/or prostate specific antigen 4ng/ml or greater underwent TRUS 13 cores prostate biopsy.that was,in addition to standard sextant biopsies,cores were taken from the far lateral and middle regions of the gland as described by Eskew.Pathological findings of the additional regions were compared with those of the sextant regions. Results:Of the patients, 39% had cancer on biopsy (20/51).Of the 20 patients with prostate caner,5(25%) would have been undetected when the sextant biopsy technique was used alone (P<0.05).No one of severe complications could be found among the patients who underwent TRUS 13 cores prostate biopsy.Conclusions:Our data demonstrated that TRUS 13 cores prostate biopsy could increase the cancer detection rate significantly.This technique is safe and efficacious,and should be recommended for clinical use.