摘要
目的 :旨在观察奥美拉唑与西米替丁治疗上消化道隆起性病变切除术后溃疡创面的愈合率、缓解疼痛及预防出血的作用。方法 :81例隆起性病变均采用高频电凝切除术 ,术后随机分为 2组 :治疗组口服奥美拉唑2 0mg ,2次 /d ,对照组口服西米替丁 40 0mg ,3次 /d。服药期间观察胸骨后 ,上腹部疼痛及有无出血、穿孔并发症。结果 :治疗组溃疡创面愈合率为 95 .2 4% ,对照组为 71.9%。 (P <0 .0 1) ;治疗组 1周内有疼痛者 9例 ,对照组为 2 1例。两组有显著性差异 (P <0 .0 1) ;治疗组 1周内出血 1例 ,而对照组有 6例 ,两者差异显著 (P <0 .0 1)。结论 :在上消化道隆起性病变切除术后 。
Objective:To compare postoperative lesion healing,pain relieving,bleeding prophylaxis of cimetidine and omperazole after high frequency electrocoagulatomy for upper gastrointestinal protbernt lesions.Methods:Eighty-one patients with upper gastrointestinal protuberant lesions were divided into two groups randomly after high frequency electrocoagulatomy.The therapy group take omperazole 20mg twice a day orally while the control take cimetidine 400mg four times a day.Complications such as poststenal and epigastric pain,bleeding,perforation were noted.Results:Lesion healing rate in therapy group was higher than control (95.42 vs 71.9,P<0.01),but less frequency of postoperative pain (9/42 vs 21/39,P<0.01)and bleeding(1/42 vs 6/39,P<0.01)within a week.Conclusions:Omperazole prescciption should be a routine therapy after high frequency electrooagulatomy for upper gastrointestinal protuberant lesions.EFFE
出处
《中国内镜杂志》
CSCD
2001年第3期9-10,共2页
China Journal of Endoscopy
