微小心肌梗塞的诊断与预后

Diagnosis and prognosis of the minor myocardial infarction

目的 通过测定血清心脏肌钙蛋白I(cTnI)结果 ,检出不稳定性心绞痛 (UA)患者中微小心肌梗塞病人 ,并判断其对预后的影响。方法 用免疫色谱法测定 90例UA患者血清cTnI ,并将其分为cTnI阳性组和cTnI阴性组 ,两组患者接受相同药物治疗 ,观察两组住院期间急性心肌梗塞、心脏性死亡的发生率。结果 90例UA患者中cTnI阳性者 2 5例 (2 8% ) ,cTnI阴性者 6 5例 (72 % )。住院期间cTnI阳性组急性心肌梗塞、心脏性死亡发生率显著高于cTnI阴性组 (P <0 .0 1)。结论 cTnI可以敏感和特异地检出UA患者中微小心肌梗塞患者。

Objective To select the minor myocardial infarction patients from unstable angina (UA) patients through the measuring of serum cardiac troponin I (cTnI) and evaluate it's prognosis value. Methods The serum cTnI of 90 UA patients were measured by immuno-chromatography, and the patients were divided into cTnI positive group and cTnI negative group. The two group patients were treated with the same drugs. The incidence of acute myocardial infarction and cardiac death were observed in the two groups during hospitalization. Results There were 25 cases of cTnI positive (28%) and 65 cases of cTnI negative (72%)in 90 UA patients. During hospitalization,the incidence of acute myocardial infarction and cardiac death in the cTnI positive group was significantly higher than that of negative group (P<0.01). Conclusion The cTnI is very sensitive and specific for diagnosis of the minor myocardial infarction in UA patients. The minor myocardial infarction indicate the increase of risk factor of bad prognosis.