严重烧伤病人康复期的微循环研究

A Study on Microcirculation in Severe Burnt Patients During Resorption Peroid

目的通过观测重烧伤康复期的微循环变化 ,探讨大面积严重烧伤对人体微循环的远期影响。方法用WX -753B型微循环显微镜及其图像处理系统 ,观测48例处于烧伤康复期患者的足甲襞微循环。本组既往烧伤的面积是(54.59±17.30) % ,年龄为(25.21±9.27)岁。伤面痊愈后1～10年 ,平均(4.71±4.50)年 ;对照组是50例健康成人 ,年龄为(24.40±4.68)岁。结果与对照组比较 ,烧伤康复期病人足甲襞微循环突出的改变是管襻畸形率高 (P<0.01)和汗腺导管数明显增多 (P<0.01) ,同时还存在血管管襻周围有渗出 (P<0.01)等 ,其余指标无显著性变化。结论严重烧伤创面虽然痊愈 ,但痊愈后的康复期仍存在微循环紊乱 ,说明严重烧伤对人体微循环影响是长期的。

Objective To study the future effect of large burnt area on microcirculation in the patients. Method The foot nailfold microcirculation(FNM) was observed from 48 cases with microcirculation microscopy and image system during the peroid of resorption in the burnt patients. The patients with burnt area of 54.6%± l7.5% and the average age of 25.2±9.27 were obtained from 1 to 11 years after resorption on the spot. 50 healthy adults were taken as a control group.Result Characteristic changes of FNM are high rates of deformed 1oops(P<0.01). The number of sweat gland ducts increase significantly (P<0.01) and permeation is found around the loops(P<0. 05). Conclusion Disorder of microcirculation was found in severe burnt patients during resorption peroid. It suggests that severe burn affects microcirculation in long term.