非淋菌性泌尿生殖道炎支原体检测及药敏分析

Mycoplasma Detection of the OPD patients with Non-gonococcal Genitourinary Tract Infection and Drug Sensitive Analysis of 6 Antibiotics

目的 :了解支原体在性病患者中的感染及耐药情况。方法 :应用支原体鉴定定量和药敏试条 ,对 12 5 2 8例怀疑性病患者 ,分成 5个年龄组取材做支原体培养和药敏试验。结果 :在这些患者中 ,支原体阳性率为 75 .3%( 9433/ 12 5 2 8) ,其中解脲脲原体 (Uu) 5 8.3%( 730 5例 ) ,显著高于人型支原体 (Mh)阳性率 3.0 %( 379例 )和Uu +Mh阳性率 14 .0 %( 1749例 ) ,阳性率比较P <0 .0 1;药物不敏感情况依次为 :氧氟沙星 5 0 .5 %、红霉素 41.9%、四环素 14 .6 %、强力霉素 4.7%、交沙霉素 2 .9%和原始霉素 2 .0 %。结论 :非淋菌性泌尿生殖道炎仍以Uu感染为主 ,集中于 2 1～ 40岁 ;支原体感染药物不敏感情况严重 ;同时进行支原体培养和药敏实验对临床用药具有重要意义。

Objective: To explore the infection of mycoplasma in the venereal diseases and information about their drug susceptibility. Methods: Materials from the 12 528 patients were cultivated and drug susceptibility made testing was made using the mycoplasma IST Kit. Results: The results showed that 9433 of 12 528 (75.3%)were infected by mycoplasma, Uu infective rate 58.3 % (7 305 cases)was found significantly higher than Mh infective rate 3.0%(379 cases)and mixed infection of both Uu and Mh was 14.0%(1 749 cases,)P<0.01. The no susceptible conditions were in turn that ofloxacine(50.5%), Erythromycine(41.9%), tetracycline(14.6%), doxycycline(4.7%), josamycine(2.9%), and pristinamycine(2.0%) respectively. Conclusions:The results suggested that non-gonococcal genitourinary tract infection was firstly ureaplasma urealyticum, concentracted infection was at age 21-40 years. no susceptible stat of mycoplasma infection to drug was serious, so that susceptibility testing of mycoplasma had a important significance to clinical drug treatment.