ADA、CEA、CA对癌性与结核性胸水的鉴别

Discrimination between Carcinous and Tuberculous Pleural Effusion with ADA、CEA、CA

目的 探讨腺苷脱氨酶 (adnosinedeaminase ,ADA)、癌胚抗原 (carcinoembryonicantigen ,CEA)、糖类抗原(carbohydrateantigen ,CA)对癌性与结核性胸水的鉴别意义。 方法 对 3年来确诊的结核性胸水 5 3例、癌性胸液 43例患者的胸水标本进行检测。结果 在结核性胸液中 ,ADA均值显著高于其在癌性胸水中的均值 (P <0 .0 1) ,而且检测的敏感性、特异性和准确性较其他指标均高 (P <0 .0 1)。在癌性胸液中 ,CEA、CA5 0、CA12 5、CA199、CA2 11的均值较它们在结核性胸液中的均值显著升高 (P <0 .0 1,P <0 .0 5 )。结论 在癌性与结核性胸水的鉴别中 ,对ADA和CA2 11的联合检测 。

Objective To appraise the relationship and discriminate the difference between the tuberculous and the carcinous pleural effusion with Adenosine Deaminase (ADA) Carcinoembryonic Antigen(CEA) and Carbohydrate Antigen(CA).Methods We have examined the samples of 53 cases of tuberculous and 43 cases of carcinous pleural effusion from patients diagnosed in recent three years.Results In tuberculous pleural effusion ,not only the average value of ADA was marked higher than in carcinous( P <0.01),but also the highest in sensitivity?speciality and accuracy( P <0.01). In carcinous pleural effusion,the average value of CEA?CA50?CA125?CA199 and CA211 were higher than those in tuberculous( P <0.01, P <0.05).Conclusion It was a much worthy way for us to distinguish which was carcinous or tuberculous pleural effusion -combined with the ADA and CA211 examination.