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RNA结合蛋白与人类男性不育 被引量:1

RNA—Binding Proteins and Human Male Infertility
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摘要 本文概括了控制精子正常产生的诸多候选基因在染色体上的定位、演化及其编码的 RNA 结合蛋白与人类男性精子发生之间关系研究方面的最新进展,为人类男性不育症的治疗和计划生育的顺利推行奠定了坚实的理论基础并展示出光明的前景。 The latest development of the research of many candidate genes controlling normal sperm with micro—deletions has been summarized in this article;Mapping their loci,explaining their evolution and exploring the relation between RNA—binding proteins they encode and male infertility are involved as well.This will lay theoretically solid foundation for and bring light upon the therapy of human male infer- tility and family planning.
作者 崔映宇 余龙
出处 《阜阳师范学院学报(自然科学版)》 2001年第2期13-16,共4页 Journal of Fuyang Normal University(Natural Science)
关键词 RNA结合蛋白 人类男性不育 无精因子 RNA结合基序 SRGY盒 AZF 遗传缺陷 RNA-binding proteins Human male infertility Azoospermia factor(AZF) RNA-binding motif SRGY box
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同被引文献11

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  • 6Elliott DJ,Oghene K,Makarov G,et al.Dynamic changes in the subnuclear organisation of pre-mRNA splicing proteins and RBM during human germ cell development[J].J Cell Sci,1998,111(9):1255-1265.
  • 7AnYu Zhou,Alexander C.Ou,Aeri Cho,et al.Novel Splicing Factor RBM25 Modulates Bcl-x Pre-mRNA 5' Splice Site Selection[J].Molecular and Cellular Biology,2008,28(19):5924-5936.
  • 8Arun P Sikarwar,Murali K Rambabu,K V R Reddy.Differential regulation of gene expression in mouse spermatogonial cells after blocking c-kit-SCF interaction with RNAi[J].RNAi Gene Silenc,2008,4(1):302-311.
  • 9Sabrina Basciani,Gabriele De Luca,Susanna Dolci,et al.PDGFR-β Regulates Proliferation and Migration of Gonocytes[J].Endocrinology,2008,149:6226-6235.
  • 10段稳铭,张清媛,程凤锐,刘相冬,王滨有.RBM1基因与无精少精男性不育的关联[J].疾病控制杂志,2002,6(1):9-12. 被引量:1

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