经直肠超声检查前列腺癌100例

Transrectal ultrasound examination of the prostate in 100 cases of prostate cancer

目的 评价经直肠超声 (TRUS)检查前列腺癌 (PCA)的临床价值。方法 回顾性分析TRUS检查并经穿刺活检证实的 10 0例PCA声像图和临床资料。结果 5 9例声像图显示为单发癌肿 ,17例为弥漫性癌肿 ,其中 35例PCA瘤体最大径线≤ 1.5cm。TRUS对前列腺癌的诊断率为 76 .0 % ,特异性 89.4% ,假阳性率 10 .6 % ,阴性预测值 88.9%。前列腺特异抗原 (PSA)随癌肿最大径线增加而升高 (P <0 .0 5 ) ,且低分化组PSA明显高于高分化组 (P <0 .0 5 )。结论 TRUS操作方便 ,无需特殊准备 ,有助于提高早期PCA的确诊率。

Objective To evaluate the clinical value of transrectal ultrasound (TRUS) examination of the protate in the diagnosis of prostate cancer (PCA).Methods The sonographic and clinical data of 100 patients with PCA were analyzed retrospectively.Results There was single lesion in 59 patients, diffuse lesion in 17 patients. The size of tumor in 35 patients was ≤1.5 cm. TRUS in the diagnosis of PCA had an accuracy of 76.0%, specificity of 89.4%, false positive rate of 10.6% and negative predictive value of 88.9%. The level of prostate specific antigen (PSA) increased with the increase in the size of the tumor ( P <0.05).The PSA level of patients with poorly differentiated PCA was significantly higher than that in patients with well differented PCA.Conclusion TRUS examination is a convenient procedure for the diagnosis of PCA in its early stage.