山莨菪碱治疗高原肺水肿疗效分析

Effects of Anisodamine on Patients with High Altitude Pulmonary Edema

目的 探讨山莨菪碱对高原肺水肿的治疗效果。方法 对 6 4例高原肺水肿的住院患者 ,进行常规治疗或在常规治疗的基础上加用静脉注射山莨菪碱 ,观察患者肺部罗音消失时间、胸片阴影消失时间、临床治愈时间。结果 6 4例患者中 ,山莨菪碱组的肺部罗音消失时间、胸片阴影消失时间及临床治愈时间较常规治疗组明显缩短 (P <0 .0 1)。结论 山莨菪碱对高原肺水肿有明显的辅助治疗作用。

Objective The aim of this study was to investigate the effect of anisodamine on patients with high altitude pulmonary edema (HAPE). Method In the present study, sixty and four hospitalized patients suffering from HAPE were treated by routine methods with or without using anisodamine and disappearing time of rales of lung and disappearing time of shadow of chest X-ray and course of illness were observed. Result The results showed that disappearing time of rales of lung and disappearing time of shadow of chest X-ray and course of illness were significantly shorter in HAPE patients treated with anisodamine than in the patients without anisodamine (P<0.01). Conclusion The study suggested that anisodamine might be an effective auxiliary medicine in treatment of HAPE.