心脏瓣膜置换术患者血糖的动态变化

Dynamic Changes of Blood Glucose of Patients under Heartvalve Replacement Operation

目的 探讨体外循环心脏瓣膜置换术时机体葡萄糖耐受能力的变化。方法 对 5 6例心脏瓣膜置换病人术前、术中、术后 12h ,2 4h ,48h的血糖水平进行了动态观察。结果 体外循环心脏瓣膜手术期间血糖明显增高 ,增高的程度与转流时间相关。结论 手术过程中有效控制病人的血糖浓度 ,可以避免围手术期并发症的发生。

Objective To probe the changes in blood glucose toleration during heart-valve replacement operation under cardiopulmonary bypass (CPB). Method Dynamic surveys of blood glucose levels of 56 cases were carried out 12 hrs, 24 hrs and 48 hrs before the operations, during them and after them respectively, and were measured by spectrophotometry. Result The glucose levels in blood from patients with heart-valve metathesis operation were 9.2±0.51 μmol/L(CPB 60 min) and 12.4±0.62 μmol/L(CPB 120 min) respectively, which were significantly higher than normal (5.3±0.47)μmol/L and 5.6±0.53 μmol/L(P<0.05). The glucose levels rose noticeably and the extent was in relation to CPB time. Conclusion An effective control over the glucose concentration helps to prevent complication during peri-operations.