摘要
作者报道了病毒性肝炎30例、冠心病19例,缺血性脑血管病14例,总计63例患者的因子Ⅷ相关抗原(vWF:Ag)、因子Ⅷ促凝活性(Ⅷ:C)及其比值(vWF:Ag/Ⅷ:C)测定结果。表明了在这三种疾病中Ⅷ:C无明显增高,vWF:Ag以及vWF:Ag/Ⅷ:C增高显著;尤其在疾病活动期或重症病人中,vWF:Ag/Ⅷ:C增高更为突出,同时可有Ⅷ:C的下降。提示本测定可作为病毒性肝炎、冠心病、缺血性脑血管病病变程度以及判定高凝状态的一种重要的非特异性指标。作者还对于这三种疾病中vWF:Ag、Ⅷ:C变化的机理进行了初步探讨。
We report the results of factor Ⅷ-associated antigen(vWF: Ag)and its coagulative activity(Ⅷ: C) and vWF: Ag/Ⅷ: C value in 63 patients (30 virus hepatitis and 19, coronary heart disease arid 14, ischemic cerebravascular disease). The results showed that there were no significantly increase in Ⅷ: C, while vWF: Ag and vWF: Ag/Ⅷ: C obviously raised, vWF: Ag and vWF Ag/Ⅷ: C more obviously raised at active stage and in severe cases. meanwhile Ⅷ: C descend. It is suggested that the determination could act as an important nonspecific index of pathalogical degree of virus hepatitis, coronary heart disease and ischelnic cerebravaseular disease and judge of hypercoagulation The preliminary evaluation of the change mechanism of vWF: Ag and Ⅷ: C in the three disease is also made.
