甘利欣联合保胆健素治疗黄疸型肝炎疗效观察

The curative effects of dyskinebyl combined diammonium glycyrrbizinate in icteric hepatitis

目的观察甘利欣联合保胆健素治疗黄疸型肝炎临床疗效。方法117例黄疸型肝炎病人应用甘利欣联合保胆健素治疗74例(治疗组) ,用甘利欣治疗43例(对照组)。比较临床症状(乏力、纳差、腹胀)和血清总胆红素(SB)、谷丙转氨酶(ALT)的复常率。结果治疗组临床症状复常率分别为75.7 %、74.3 %、68.9 % ,与对照组53.5 %、53.5 %、46.5 %比较有显著性差异(P<0.05) ;治疗组SB、ALT复常率分别为70.0 %、72.9 % ,与对照组48.8%、48.8 %比较有非常显著性差异(P<0.01) ;两组综合疗效治疗组总有效率为89.2% ,与对照组62.8 %比较有非常显著性差异(P<0.01)。结论甘利欣联合保胆健素治疗黄疸型肝炎疗效显著 ,是有效、方便的疗法 ,值得推广应用。

Objective To observe the effects of dyskinebyl combined diammonium glycyrrbizinate (DG) in treating icteric hepatitis. Methods 117 cases patient with icteric hepatitis were divided into two groups, the treat group (74 cases) were treated with dyskinebyl combined DG. The control group were treated with DG. The clinical symptoms (malaise, anorexia, abdominal distension) and SB, ALT were observed and compared between two groups during treatment. Results The recovery rate of clinical symptoms were 75.7%, 74.3%, 68.9% in treat group and 53.5%, 53.5%, 46.5% in control group, there were a significant difference betweem two groups(P<0.05). The recovery rate of SB, ALT were 70.0%, 72.9% in treat group, and 48.8%, 48.8% in control group. There was a marked signifiant difference betweem two groups (P<0.01). The total effective rate in treat group (89.2%) was highter than that in control group (62.8%) (P<0.01). Conclusion The dyskinebyl combined DG was a markedly effective in icteric hepatitis and less side_effect.