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血浆可溶性细胞间粘附分子-1:不稳定型心绞痛时炎症反应的指标 被引量:1

Plasma Soluble Intercellular Adhesive Molecule-1: An Index of Inflammatory Reaction in Unstable Angina
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摘要 越来越多证据表明炎症在不稳定型心绞痛的发生发展中起着非常重要的作用 ,细胞间粘附分子 1是白细胞整合素CD18家族的主要配体 ,介导着白细胞与激活的内皮细胞间粘附 ,从而介导炎症反应。本文检测 15例不稳定型心绞痛 (UA) ,16例稳定劳力型心绞痛 (SEA)及 15例健康者血浆可溶性细胞间粘附分子 1(sICAM 1)的浓度。UA组血浆sICAM 1水平 (ng/ml)比SEA组以及健康对照组明显升高 (181± 12vs 139± 7,131± 9,P <0 .0 5 )。结果表明UA患者循环中sICAM 1水平升高支持炎症反应在UA中的病理作用。检测sICAM 1可作为炎症引起的UA的有用指标。
作者 闵新文
出处 《内科急危重症杂志》 2001年第2期75-76,共2页 Journal of Critical Care In Internal Medicine
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