青蒿素母液体外抗真菌试验

Antifungal Test of Artemisinine Mother Solution Outside Body

用5％青蒿素母液、苯甲酸、水杨酸、6％青蒿素渣煎剂和青蒿素渣粉剂对3种霉菌及酵母菌进行体外生长抑制试验；再用2％、1％、0．5％、0．25％、0．125％的青蒿素母液及苯甲酸，采用平皿纸片扩散法对3种霉菌及酵母进行体外抑菌试验，并与空白和溶剂对照。结果表明：青蒿素渣粉剂和煎剂对部分真菌有不同程度的抑制作用，5％母液对所试真菌抑制作用均很强，与5％苯甲酸和水杨酸相当。青蒿素毒母液在浓度高于20％时对所试真菌有较强抗菌作用，其作用苯甲酸相当（P＞0．05），而低于20％时抑菌效果不明显。

The 5％ Artemisinine mother solution Benzoic acid and Salicylic acid、 6％ Artemisinine decocta and Artemisinine pulveres were used to do the growing and controling test outside body against three kinds of mold and yeast． Then another experiment was done by using 2％、1％、0．5％、 0．25％、 0．125％ Artemisinine mother solution and Benzoic acid． Compare with those of the blanks and solvents, the results suggest that Artemisinine decocta and pulveres have antifungal effects on some degree, 5％ mother solution show strong effect, similiar with 5％ Benzoic acid and salicylic acid． when the concentration was over 20％ the Artemisinine mother sdution could prevent fungus significantly, similiar with Benzoic acid P＞0．05, Otheruise, it was not obvious．