糖尿病患者视觉诱发电位分析

Pattern reversal visual evoked potentials analysis in patients with noninsulin dependent diabetes mellitus

目的 :探讨非胰岛素依赖型糖尿病 (又称Ⅱ型糖尿病 )患者视觉诱发电位 (PVEP)的改变及临床应用价值。方法 :对 30例 (6 0只眼 )Ⅱ型糖尿病患者和 30例 (6 0只眼 )正常对照组进行PVEP检测。结果 :糖尿病组PVEP的异常阳性率为 5 8 33% ,表现为P10 0潜伏期明显延长 ,波形分化差 ,波幅低。结论 :PVEP的异常可作为糖尿病患者视功能早期观察指标之一 ,PVEP的异常与空腹血糖、糖尿病的病程长短。

Objective To explore the alteration of pattern reversal visual evoked potentials (PVEPs) in patients with noninsulin dependent diabetes mellitus (NIDDM) and its values in clinical application. Methods PVEPs were recorded in 30 cases with NIDDM and 30 cases of normal individuals. Results The abnormal rate of PVEPs in patients with NIDDM was 58.33%, and the latency of P100 was markedly prolonged. The waveforms were poor differentiated, and the amplitudes of waves were low.Conclusion Abnormal PVEPs can be regarded as one of the index of visual function in patients with NIDDM. The abnormality of PVEPs is related to blood sugar in empty stomach, course of NIDDM, peripheral nerve lesions and diabetic retinopathy.