摘要
目的 :探讨静注卡托普利 (CPT)治疗高血压病伴左心功能不全的疗效。方法 :根据卡托普利10 m g和 2 0 m g分为 A、B两组 (A组 2 0例、B组 35例 ) ,观察治疗前后心率、平均动脉血压和心功能改善情况 ,并对 A组中 16例用药前后作血管紧张素 、醛固酮水平测定。结果 :静注 CPT后患者心率减慢、平均动脉血压下降、心功能改善 ,血管紧张 和醛固酮水平显著降低 (P<0 .0 1) ,给药剂量和疗效平行。结论 :静注卡托普利是临床治疗高血压病伴心功能不全的有效手段。
Objective: To observe the therapeutic effect of CPT injection on left ventricular dysfunction caused by hypertension. Methods: 55 patients of left ventricular dysfunction caused by hypertension were randomily divided into two groups: group A was treated with CPT 10mg and group B 20mg. Heart rate? MAP? AngⅡ and Ald were measured before and after treatment. Results: Heart rate? MAP? AngⅡ and Ald significantly decreased (P<0.01) and heart function was improved. Conclusions: CPT injection can effectively treat left ventricular dysfunction caused by hypertension.