静肤平中甲硝唑与红霉素的含量测定

Determination of metronidazolum and erythromycin in Jing-fu-ping liqour

目的 :建立用比色法与分光光度法测定静肤平中红霉素、甲硝唑含量的方法。方法 :以稀盐酸 (910 0 0 )溶液为溶剂 ,在 4 17nm ,2 77nm波长处进行测定。结果 :红霉素在 5 0～ 2 0 0 μg/ml浓度范围内线性关系良好。红霉素的平均回收率为 98 55% ,RCD为 0 52 % (n =5) ,甲硝唑的平均回收率为 98 86 % ,RCD为 0 51% (n =5)。结论 :本方法简便快捷、准确 。

OBJECTIVE:To estabish a quantiative analysis for Jing fu ping liqour.METHODS:Jing fu ping liquor was determined in 0.1mol/L HCl.The wavelength of detection were 417nm and 277nm.RESULTS:There were good linear correlation in the range of erythromycin(5 0～20 0μg/ml) and metronidazolum(2 0～15 0μg/ml),the average recovery and relative standard deviation were 98 55% and 0 52%( n =5) for erythromycin 98 86% and 0 51%( n =5) for metronidazolum.CONCLUSIONS:The method is simple,rapid and auurate.