倍美力对绝经后妇女血脂影响的临床研究

Clinical study on blood-lipid of postmennopausal women treated with Beimeili

目的：研究倍美力对绝经后妇女血脂蛋白的影响。方法：选择100例绝经后妇女，随机分为治疗组和对照组，其中治疗组50例，每日口服倍美力0.625mg，对照组50例，每日口服一片安慰剂。结果：用药3个月后其治疗组apo-AL，HDL-C显著升高，其次为LDL-C的下降，用药12个月后apo-AL，HDL-C仍较对照组显著升高，LDC-C显著下降；治疗组仅有一例发生心绞痛，为2%，明显低于对照组。结论：倍美力替代女性激素以防治冠心病是极为有效的。

Objective: To study the effect of Beimeili on the blood lipoprotein of postmenopausal women. Method: One hundred postmenopausal women were randomisedly divided into a treatment group and a control one. The 50 cases in the treatment group were given Bei meili orally 0.625mg/d. And another 50 cases in the control group were given a tablet of placebo daily. Result: After 3 months' medication, the apo-AL and HDL-C and HDL-C of the treatment group increased notably while the LDC-C decrease markedly. The apo-AL and HDL-C were still notably higher than those of the control group after 12 month's medication. And the LDC-C was still markedly lower than that of the control group. Only one case of angina pectoris occurred in the treatment group (2%), which was markedly lower than that of the control group. Conclusion: It is extraordinarily effective to replace estrogen with Beimeili in the prevention and treatment of coronary heart disease.