补碘对缺碘机体血清超氧化物歧化酶水平的影响

Effects of iodine supply on the level of serum superoxide dismutase in inodine deficiency bodies

目的 探讨补碘对缺碘机体抗氧化能力的影响。方法 观察了缺碘地区人群口服碘油前后外周血超氧化物歧化酶（ＳＯＤ）水平的改变。结果 补碘之前，缺碘机体的血清ＳＯＤ水平高于正常对照组水平；补碘３～６个月之后其血清ＳＯＤ水平高于服药前的水平，３个月时其高于上限的比例显著增多，至１２个月时则显著减少。结论：补碘可导致缺碘机体ＳＯＤ水平升高，以增强机体的抗氧化能力。

Objective To study the effects of iosine supply on antixidative ability in iodine deficiency bodies. Methods The lecles of serum superoxide dismutase(SOD) were continuously observed before and after administrering oral iodized capsule. Results The levels of serum SOD before supplying iodine were higher than thaose of control. Serum SOD levels after supplying iodine for three to six months were higher than that before iodine supply. Proportion of SOD which exceed upper limit after supplying iodine for three months was increased markedly, but it was decreased significantly for twelve months. Conclusions Supplying iodine for the bodies with iodine deficiency might result in rising levels of SOD, so that it could to strengthen antioxidative ability of body.