大脑中动脉闭塞的超选择性动脉内溶栓治疗

Superselected intra-arterial thrombolytic therapy for acute middle cerebral artery occlusion

目的 :探讨超选择性动脉内溶栓治疗急性大脑中动脉闭塞的价值。方法 :经股动脉穿刺 ,将微导管超选择插至闭塞血管远端或置于血块内注入尿激酶 (UK)进行溶栓治疗。 12名急性大脑中动脉闭塞患者接受了溶栓治疗。结果 :8例获得大脑中动脉完全再通 ,3例获得部分再通 ,1例没有发生再通。随访 5个月 ,6人生活能完全自理 ,2人生活部分自理 ,3人无法生活自理 ,1人死亡。结论 :超选择性动脉内溶栓治疗可作为急性大脑中动脉闭塞可供选择的治疗方法之一。

Objective:To evaluate the superselective intraarterial thrombolysis for acute middle cerebral artery occlusion.Methods:A microcatheter was introduced into the proximal end of the occluded artery or placed into the clot for thrombolysis.By which,12 patients with acute middle cerebral artery occlusion were treated.Urokinase was used as the thrombolytic agent.Results:Middle cerebral artery occlusion was restored in 8 cases,partially restored in 3 ones and not restored in one case.Following up for five months,6 patients took care of themselves,2 were partial self care,3 were not self care,and 1 died.Conclusion:Superselective intraarterial thrombolytic therapy is a method of choice in therapy for acute stroke.