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分枝杆菌ESAT-6研究进展 被引量:6

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摘要 ESAT- 6即 6k Da早期分泌性抗原性靶 ,是从结核杆菌短期培养滤液 (ST- CF)中纯化分离出的一种低分子量分泌性蛋白 ,具有较强的细胞免疫活性 ,在抗结核感染的免疫回忆应答中起重要作用 ;由于编码 ESAT- 6的基因在卡介苗 (BCG)各菌株中缺乏 ,ESAT- 6可望成为人和动物结核病的特异性诊断试剂、抗结核亚单位疫苗的组分和
出处 《国外医学(预防.诊断.治疗用生物制品分册)》 2001年第4期145-147,共3页 Foreign Medical Sciences(Section of Bilogics for Prophylaxis,Diagnosis and Therapy)
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  • 1Andersen P et al.J Immunol,1995;154:3359-3372
  • 2Sorensen AL et al. Infect Immun,1995;63:1710-1717
  • 3Harboe M et al. Infect Immun,1996;64:16-22
  • 4Brandt L et al. J Immunol,1996;157:3527-3533
  • 5Ravn P et al. J Infect Dis,1999;179(3):637-645
  • 6Charron D . Genetic diversity of HLA functional and medical implication. In: Charron D eds. Anthropology:Contribution of HLA. Sevres,France:Medical and Scientific International Publisher, 1997: 344-353
  • 7Fort M et al. Tissue Antigens ,1998 ; 51: 327-336
  • 8Friscia G et al. Clin Exp Immunol ,1995 ;102 : 53-57
  • 9Direskeneli et al. Scand J Immunol,1996;43:464-471
  • 10Pollock JM et al. Immunology,1994;82:9-15

同被引文献58

  • 1朱中元,王海波,刘爱国,谢勇.抗结核分枝杆菌多种抗原的抗体检测蛋白芯片研究[J].中国热带医学,2004,4(6):907-910. 被引量:32
  • 2高源,万康林.结核分支杆菌蛋白抗原研究进展[J].中国媒介生物学及控制杂志,2005,16(1):74-77. 被引量:7
  • 3顾田园,蔡宏,田霞,余大海,朱玉贤.结核分枝杆菌四价DNA疫苗免疫原性和保护效率研究[J].生物化学与生物物理进展,2005,32(4):347-352. 被引量:6
  • 4Gennaro M L.Immunologic Diagnosis of Tuberculosis[J].Clinical Infectious Diseases,2000,30(suppl3):s243-s246.
  • 5Shinnick T M.Diagnosis test needs for evaluating antituberculosis vaccines[J].Clinical Infectious Diseases,2000,30(Supp13):276-278.
  • 6Buddle B M.Use of easat-6 in the IFN-γtest needs for evaluating antituberculosis vaccines[J].Vet Mcrobiology,2001,80:37-46.
  • 7Harboe M,Cettinger T,Wiker HG,et al.Evidence for occurrence of the ESAT-6 protien in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG[J].Infect Immune,1996,64:16-22.
  • 8Haslov K,Andersen AB,Ljungqvist L,et al.Comparison of the immunological activity of five defined antigens from Mycobacterium tuberculosis in seven inbred guinea pig strains.The 38-Kda antigen is immunodominant[J].Scand J Immun,1990,31(4):503-504.
  • 9Wilkins EG,Ivanyi J.Potential value of serology for serology for diagnosis of extrapulmonary tuberculosis[J].Lanct,1990,336(8716):614-644.
  • 10Dillon DC,Alderson MR,Day CH,et al.Molecular and immunological characterization of Mycobacterium tuberculosis CFP-10,An Immunodiagnostic Antigen Missing in Mycobacterium bovis BCG[J].clin mlcrobiol,2000,38(9):3285-3290.

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