摘要
目的 :观察广痛消泡沫气雾剂对小鼠和大鼠的镇痛及解痉作用。方法 :采用小鼠扭体法、大鼠甩尾法和直肠平滑肌体外收缩生理仪描计法。结果与结论 :广痛消泡沫气雾剂 18.75 ,12 .5 0g·kg-1灌胃后 ,能明显提高小鼠化学刺激和大鼠物理刺激后的痛阈 。
Objective:To observe the analgesic and antispa smodic effects of Guang Tong Xiao Aerosol(GTXA). Method: Writhing test and tail-flick of physical stimulation were made to study the a nalgesic effect on mice and rats.Result and Conclusion: GTXA given by gastr ogavage in dose of 18.75 g·kg -1 or 12.50 g·kg -1 could markedly ra ise the pain threshold after chemical stimulation in mice and physical stimula tion in rats ,and had antispasmodic effects. [Key words] Guang Tong Xiao;aerosol; analgesic;antispasmod ic 2-dimethy-3-(p-methoxy-benzene-sulfony l)imidazolinium iodid.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2001年第8期559-561,共3页
China Journal of Chinese Materia Medica
关键词
广痛消
泡沫气雾剂
镇痛
解痉
Guang Tong Xiao
aerosol
analgesic
antispas modic
