全胃肠外营养对妊娠剧吐及妊娠结局的影响

The effect of total parenteral nutrition on hyperemesis gravidarum and pregnancy ending

目的探讨全胃肠外营养 (TPN)疗法在妊娠剧吐中的作用及其对妊娠结局的影响。方法采用 TPN疗法治疗妊娠剧吐 2 7例与30例常规输液 ,纠正水电解质、酸碱平衡疗法对比观察止吐效果 ,尿酮体转阴时间及妊娠结局。结果 TPN治疗 3天止吐率 5 5 .6 % ,酮体转阴时间 (3.1± 0 .84)天 ,新生儿体重 (3.4± 0 .38) kg,对照组分别为 13.3%、(5 .2± 1.0 6 )天、(2 .9± 0 .45 ) kg,两组间有显著性差异 (P<0 .0 5 ) ;流产、死胎率比较及难产率、新生儿评分两组间无显著性差异 (P>0 .0 5 )。结论 TPN在妊娠剧吐中有良好疗效 ,可增加新生儿体重 。

Objective To evaluate the effect of total parenteral nutrition (TPN) on hyperemesis gravidarum (HG) and pregnancy ending.Methods 27 cases of HG were treated with TPN and 30 cases with the routine infusion to adjust water electrolyte and acid base balance for the purpose of observation of vomiting stopping,time of turning ketonic negative and pregnancy ending.Results After 3 day treatment with TPN,stopping vomiting rate was 55.6%,time of turning ketonic negative was (3.1±0.84) days and neonatal weight was (3.4±0.38) kg,which was 13.3%,(5.2± 1.06) days and (2.9±0.45) kg respectively in control group.There was significant difference between the two groups (P<0.05),but no significant difference was found in comparison of miscarriage and fetal death rate as well as dystocia rate and neonatal scoring between the two groups (P<0.05).Conclusion TPN has a good effect on HG and no side effect on pregnancy ending,which can increase neonatal weight.