期刊文献+

瘦素与代谢综合征 被引量:15

下载PDF
导出
摘要 大量临床试验表明 ,瘦素水平异常与胰岛素抵抗关系密切 ,甚至有作者认为高瘦素血症是代谢综合征的一个组成部分。对一些缺乏瘦素、具有胰岛素抵抗的动物模型的研究证实 ,瘦素能够纠正糖脂代谢紊乱、增加胰岛素敏感性 ,被认为是一个抗糖尿病的激素。瘦素能升高小鼠的血压 ,至于对人类血压的影响 ,研究结果尚存争议。
出处 《国外医学(内分泌学分册)》 2001年第4期195-197,共3页 Foreign Medical Sciences(Section of Endocrinology)
  • 相关文献

参考文献18

  • 1Wabitsch M;Jensen P B;Blum W F.Insulin and cortisol promote leptin production in cultured human fat cells[J],1996.
  • 2Seufert J;Kieffer T J;Leech C A.Leptin suppression of insulin secretion and gene expression in human pancreatic islets:implication for the development of adipogenic diabetes mellitus[J],1999.
  • 3de Courten M;Zimmet P;Hodge A.Hyperleptinemia:The missing link in the metabolic syndrome?[J],1997.
  • 4Segal K R;Landt M;Klein S.Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men[J],1996.
  • 5Laivuori H;Kaaja R;Koistinen H.Leptin during and after preeclamptic or normal pregnancy:its relation to serum insulin and insulin sensitivity,2000.
  • 6Tsuboyyama K N;Takahashi M;Tanemura K.Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice[J],2000(9).
  • 7Bastard J P;Jardel C;Bruckert E.Elevated levels of interleukin 6 reduced in serum and subcutaneous adipose tissue of obese women after weight loss[J],2000.
  • 8Ogawa Y;Masuzaki H;Hosoda K.Increased glucose metabolism and insulin sensitivity in Transgenic Skinny Mice overexpressing leptin[J],1999(9).
  • 9Tasaka Y;Yanagisawa K;Iwamoto Y.Human plasma leptin in obese subjects and diabetes,1997.
  • 10Bertin E;Rich N;Schneider N.Insulin and body fat distribution have no direct effect on plasma leptin levels in obese Caucasian women with and without type 2 diabetes mellitus,1998.

同被引文献151

引证文献15

二级引证文献45

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部