蓝/黄视野检查法对原发性开角型青光眼的早期诊断价值

A study of blue-on-yellow perimetry in the early diagnosis of primary open-angle glaucoma

目的 探讨蓝 /黄视野检查法 (blue- on- yellow perimetry,B/ Y PM)对青光眼的早期诊断价值。 方法 利用 OCTOPUS10 1全自动视野计 G2程序分别对 16例 (32只眼 )正常人 ,2 5例 (35只眼 )白 /白视野检查 (white- on- white perimetry,W/ W PM)异常的原发性开角型青光眼 (primary open- angleglaucoma,POAG) ,15例 (15只眼 ) W/ W视野检查正常的早期 POAG及 11例 (2 2只眼 )可疑 POAG进行B/ Y视野检查。 结果 正常人、可疑 POAG、早期、中期及晚期 POAG B/ Y视野检查视网膜平均敏感度分别为 (2 3.2 4± 1.2 2 ) d B、(2 0 .97± 3.42 ) d B、(18.44± 3.5 7) d B、(11.0 4± 1.85 ) d B及 (8.5 5± 2 .2 9) d B。B/ Y视野检查法对检测青光眼视野损害的敏感性高于常规 W/ W视野检查法 ,敏感性为 92 % ,特异性为90 .6 2 %。早期和中期 POAG中 ,B/ Y视野检测出视野缺损点数明显多于 W/ W视野检测出的缺损点数。结论 B/ Y视野检查法是检测 POAG早期视野损害的敏感方法之一。

Objective To evaluate the application of blue on yellow(B/Y) perimetry in detecting the early visual field loss of glaucoma. [WT5”HZ]Methods [WT5”BZ]The B/Y perimetry of the G2 strategy in the OCTOPUS 101 perimetry was used to examine the visual field of 16 normal persons (32 eyes), 25 cases (35 eyes) of primary open angle glaucoma (POAG) with abnormal white on white (W/W) visual fields, 15 cases (15 eyes) of early POAG with normal W/W visual field, and 11 cases (22 eyes) of suspected POAG. [WT5”HZ]Results [WT5”BZ]The mean sensitivity (MS) in the normal cases, suspected POAG, early POAG, middle POAG, and late POAG was (23.24±1.22) dB,(20.97±3.42) dB,(18.44±3.57) dB,(11.04±1.85) dB and (8.55±2.29) dB, respectively. It was demonstrated that B/Y perimetry was more sensitive than W/W perimetry in detecting the glaucomatous visual field defects,and its sensitivity was 92% and specificity was 90.62%. The average number of defective points in central visual field with B/Y perimetry was more than that with W/W perimetry in early and middle POAG. Conclusion B/Y perimetry is a relatively sensitive method for detection of the early visual field loss in POAG.