摘要
We have demonstrated that prolactin inhibits gonadotropin-induced ovulation in PMSG-primed mice.The number of ova in oviducts considerably decreased in the group of hCG plus prolactin (PRL)(19.7 + 4.9) as compared with that of hCG alone (31.7 + 6.7). PRL inhibition of hCG-inducedovulation in mice may be through decreasing the ovarian plasminogen activator (PA) activity on onehand, and inhibiting the preovulatory increase in estrogen (E) secretion on the other.
We have demonstrated that prolactin inhibits gonadotropin-induced ovulation in PMSG-primed mice. The number of ova in oviducts considerably decreased in the group of hCG plus prolactin (PRL) (19.7 + 4.9) as compared with that of hCG alone (31.7 + 6.7). PRL inhibition of hCG-induced ovulation in mice may be through decreasing the ovarian plasminogen activator (PA) activity on one hand, and inhibiting the preovulatory increase in estrogen (E) secretion on the other.
基金
The project is supported by Chinese Academy of Sciences
The State Family Planning Commission
The Natural Science Foundation of china
Rockefeller Foundation,New York.
