重型脑损伤后Terson综合征

Terson syndrome after severe brain injury

目的 研究重型脑损伤 (SBI)后Terson综合征 (TS)发生的相关因素和临床特点。 方法 监测 16 1例脑损伤病人的颅内压 (ICP)、眼内压 (IOP)、脑灌注压 (CPP)、视觉诱发电位 (VEP)和视力 ,分析它们与SBI后TS的关系。 结果 SBI后TS的发生率显著高于对照组 ;TS的发生与急性ICP和IOP增高密切相关 ,发生TS病人的ICP和IOP显著高于对照组 ;急性IOP增高与急性ICP增高呈显著正相关 ,ICP曲线上出现A波者大多发生TS。 结论 SBI后IOP和ICP明显增高的病人易发生TS ;有效控制ICP和IOP ,防止ICP曲线上A波出现 。

Objective To investigate the related factors of Terson syndrome after severe brain injury (SBI). Methods The intracranial pressure (ICP),intraocular pressure(IOP), cerebral perfusion pressure(CPP), vision and visile evoked potential(VEP) of 161 SBI patients were monitored. The relationship between these indexes and Terson syndrome was prospectively studied. Results The incidence of Terson syndrome after SBI was significantly higher than that of the control group; Terson syndrome was positively related with increase of acute ICP and IOP. The ICP and IOP of patients with Terson syndrome were significantly higher than those of the control group. The increase of acute IOP was positively related with the increase of acute ICP. Most patients with A wave in the ICP curve suffered from Terson syndrome. Conclusions SBI patients with increase of acute ICP and IOP easily suffer from Terson syndrome. It is helpful to reduce incidence of Terson syndrome by controlling ICP and IOP effectively in SBI patients.