摘要
Apolipoprotein A Ⅰ, the major protein component of the HDL, exerts its important function during modulating the metabolism of lipids in the plasma. Animal experiments have established that high concentration of the apo A Ⅰ not only inhibits the initiation and progression of atherosclerosis, but also makes the preexisting atherosclerotic lesions regress. The most accepted mechanism is reverse cholesterol transport(RCT). It may become a new non traumatic therapy that the atherosclerosis is prevented and treated by the purified or recombinant human apolipoprotein A Ⅰ.
Apolipoprotein A Ⅰ, the major protein component of the HDL, exerts its important function during modulating the metabolism of lipids in the plasma. Animal experiments have established that high concentration of the apo A Ⅰ not only inhibits the initiation and progression of atherosclerosis, but also makes the preexisting atherosclerotic lesions regress. The most accepted mechanism is reverse cholesterol transport(RCT). It may become a new non traumatic therapy that the atherosclerosis is prevented and treated by the purified or recombinant human apolipoprotein A Ⅰ.
出处
《北京大学学报（医学版）》
CAS
CSCD
北大核心
2001年第4期320-322,共3页
Journal of Peking University:Health Sciences
基金
国家重点基础研究发展规划项目(973)基金(G2000056902)&&
