复发性口疮与SOD活性关系的探讨

The relationship Between Recurrent Aphthous Stomatotitis (RAS) and Superoxide di smutase (SOD).

目的 :研究复发性口疮 (RAS)与超氧化物歧化酶 (SOD)活性的关系。方法 :选择复发性口疮患者 6 3例 ,健康成人 6 8例 ,取耳血加入蒸馏水中制成溶血液 ,用 72 2S分光光度计来测定红细胞超氧化物歧化酶活性。结果 :复发性口疮患者的SOD较健康人的SOD明显低下 (P <0 .0 1)。有显著性差异。男女之间SOD值无变化 ,(P >0 .0 5 ) ;无统计学意义。结论 :氧自由基在RAS的发病过程中可能是多因素致病的环节之一。

Objective:To investigate the correlation between RAS an d SOD. Methods:The ear bloos were collected from 63 RAS pati ents and 68 healthy controls; and the activities of erythrocyte SOD ere investig ated by the 722S spectrophotometer. Results:The SOD was lo w in the group of RAS patients. There was statistically significant difference b etween the experimental group and control group,(P<0.01), without statistica lly significant difference between the men and women(P>0.05). Con clusions:The oxygen free radicals (OFRs) would be the one of the reas ons causing RAS.