洛美沙星壳聚糖阴道栓的研制及临床观察

Study and clinical observation of Lomefloxacin and chitosan vaginal suppository

目的研制洛美沙星壳聚糖阴道栓 ,试用于临床。方法以壳聚糖、明胶、甘油为基质制备洛美沙星壳聚糖阴道栓 ,建立质量标准 ,并对其进行临床观察。结果该栓剂制备工艺可行 ,质量标准能够控制此品的质量 ,临床疗效可靠 ,无不良反应。

PurposeThe aim is to study Lomefloxacin and chitosan vaginal suppository, and to apply the preparation.MethodsLomefloxacin and chitosan vaginal suppository was prepared with chitosan, gelatine and glycerine as materials. Its qualitative standard was established, and Lomefloxacin and chitosan vaginal suppository was observed in clinic.ResultsThe prepared procedure of Lomefloxacin and chitosan vaginal suppository was practicable, and the qualitative standard is able to control the quality of this product. The clinical therapy of Lomefloxacin and chitosan vaginal suppository was reliable with none of adverse reactions.ConclusionThis preparation may be used in clinical practice.