4-氨基-β-咔啉衍生物的新合成方法

A New Synthesis of 4-Amino-β-Carboline Derivatives

报道了一种以Hantzsch反应和分子内Goldberg反应为关键步骤的 β 咔啉类化合物的新合成方法 ,并合成了两个新的 4 氨基 β 咔啉衍生物 ,包括合成反应中的 4个中间体均未见文献报道。

This paper described a new convenient synthesis of 4-amino-β-carbolines,based on the key steps such as the Hantzsch synthesis and a modified intramolecular Goldberg amidearylation.Two new 4-amino-β-carboline derivatives were synthesized.All of the intermediates and target compounds have never been reported before.