摘要
报道了合成甜菜碱的新工艺。该法通过氢氧化钙和氯乙酸的中和 ,氯乙酸钙的三甲胺化两步反应 ,最后提纯分离制取甜菜碱 ,产品甜菜碱含量达到 (98± 1) %。
The paper reported the new technology of synthesizing betaine.The betaine was synthesized by two steps,which were the neutralization reaction of Ca(OH) 2 and ClCH 2COOH,amination reaction of(CH 3) 3N and (ClCH 2COO) 2Ca,then the betaine was obtained by separation and purification.The content of the betaine reached (98±1)%.
出处
《中国药物化学杂志》
CAS
CSCD
2001年第3期160-162,共3页
Chinese Journal of Medicinal Chemistry
关键词
甜菜碱
合成
新工艺
betaine
synthesis
new technology