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nm23-H_1基因产物表达与原发性胆囊癌生物学行为及预后的关系 被引量:3

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摘要 nm23基因位于人17号染色体长臂(17q21.3),其产物为Mr 17×103的核苷二磷酸激酶(nucleotide diphosphokinase,NDPK),起抑制恶性肿瘤转移的作用,但也有与此不同的报道[1].目前nm23-H1与原发性胆囊癌转移扩散与预后的关系尚未定论.本文应用免疫组化方法观察了nm23-H1/NDPK在胆囊癌原发灶组织的表达情况,并探讨其与胆囊癌临床生物学行为与预后的关系.
出处 《中华肝胆外科杂志》 CAS CSCD 2001年第8期502-503,共2页 Chinese Journal of Hepatobiliary Surgery
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  • 1刘华,温志震,王嘉祺,居军,李永红,宋秀荣,范临夏.肺癌痰液p53和K-ras基因及端粒酶联合检测的临床研究[J].中华肿瘤防治杂志,2006,13(17):1304-1307. 被引量:4
  • 2Chung MJ, Jung SH, Lee BJ, et al. Inactivation of the PTEN gene protein product is associated with the invasiveness and metastasis, but not angiogenesis, of breast cancer[J]. Pathol Int,2004,54(1):10-15.
  • 3Iizuka N, Oka M, Noma T, et al. Nm23H1 and nm23H2 messenger RNA abundance in human hepatocellular carcinoma[J]. Cancer Res, 1995,55(3):652-657.
  • 4Gazzeri S, Brambilla E, Negoescu A, et al. Overexpression of nucleoside diphosphate/kinase A/nm23H1 protein in human lung tumors: association with tumor progression in squamous carcinoma[J]. Lab Invest, 1996,74(1):158-167.
  • 5Lee CS, Redshaw A, Boag G, et al. Nm23H1 protein immunoreactivity in laryngeal carcinoma[J]. Cancer, 1996,77(11): 2246-2250.
  • 6Marone M, Scambia G, Ferrandina G, et al. Nm23 expression in endometrial and cervical cancer:inverse correlation with lymph node involvement and myometrial invasion[J]. Br J Cancer, 1996,74(7):1063-1068.
  • 7Fujii K, Yasui W, Shimamoto F, et al.Immunohistochemical analysis of nm23 gene product in human gallbladder carcinomas[J]. Virchows Arch, 1995,426(4):355-359.
  • 8杨竹林 李永国.胆道恶性肿瘤nm23基因蛋白表达及其意义[J].中华实验外科杂志,1995,9(5):361-361.
  • 9Bresalier RS,Ho SB,Schoeppner HL, et al. Enhanced sialylation of mucin associated carbohydrate structures in human colon cancer metastasis[J]. Gastroenterology,1996,110(5):1354-1367.
  • 10Besson A, Robbins SM, Yong VW. PTEN/MMAC1 mutations in signal transduetion and tumorigenesis[J]. Eur J Biochem, 1999,263:605-611.

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