帕米磷酸二钠治疗多发性骨髓瘤的溶骨性病变的临床观察

The clinical observation of the therapeutic effectiveness of Pamidronat edisodium for osteolytic lesion induced by mutiple myeloma

目的 :探讨帕米磷酸二钠治疗多发性骨髓瘤的溶骨性病变的疗效。方法 :在 35例患者中以帕米磷酸二钠和密钙息为对照药进行对比研究。结果 :帕米磷酸二钠对多发性骨髓瘤的溶骨性病变的有效率高于密钙息 (P <0 0 1)。结论

Objective To study the therapeutic effectiveness o f Pamidronate disodium for osteolytic lesion induced by mutiple myeloma.Me thod To compare the therapeutic effectiveness of Pamidronate disodium and that of Miacalcic used as control group in 35 patients.Results t he effective rate of Pamidronate disodium for osteolytic lesion induced by mutip le myeloma is significantly higher than that of Miacalcic( P <0 01).Conclusions Better response can be gotten when Pamindronate disodium i s used in reducing the incidence of skeletal events and its complications induce d by the tumor.