五例心脏淀粉样变的临床表现及诊断分析

The Clinical Analysis and Diagnosis of Cardiac Amyloidosis

目的：探讨心脏淀粉样变的临床特点及诊断。 方法：对５例心脏淀粉样变患者的临床特点、辅助检查及确诊方法进行分析。 结果：全部患者均为多系统病变伴心力衰竭，可伴限制型心肌病表现、体位性低血压、心律失常，超声心动图示心室壁增厚而心腔大小正常。 结论：对出现以上症状、体征及辅助检查结果者，拟诊为心脏淀粉性变性，确诊靠病理学检查。

Objective:To analyse man ifestations,diagnosis of cardiac amyloid osis. Methods:The diognosis of cardiac amylo idosis was established in 5 patients by autopsy and biopsy,and their clincal man ifestations,accessory examinations and d iagnostic methods were analysed. Results:All the patients had cardiac d ysfunction.Four presented with restricti ve cardiomyopathy.Tow had postural hypot ension but hypertension previously.ECG s howed low QRS voltages,arrhythmias and i schemic ST-T changes.Echocardiography sh owed symmertrical thickness of left vent ricle but normal size of chambers. Conclusion:Cardiac amyloidosis should be suspected in patients with clinical m anifestations and examination results me ntioned above. Biopsy is required for corr ect diagnosis.