心瓣膜替换术者心肌病变与心功能的关系

THE RELATIONSHIP OF MYOCARDIAL PATHOLOGY WITH HEART FUNCTIONS IN THE PATIANTS WITH VALVE REPLACEMENT

应用自动图象分析仪定量测量了46例行换瓣术的风湿性心脏病者的心肌主要病理改变。经多元逐步回归处理,证明心肌纤维化,慢性微动脉病变与术后心功能非常显著相关。以心肌纤维化居首位,血管病变次之。同时进行了逐步判别分析,计算判别函数,可为临床提供有价值的预测指标。

In this study, image analysis technique (IAT) was used in the quantitative analysis of the essential pathological changes in the myocardium. The myocardial samples were taken from 46 patients of rheumatic heart disease, who had undergone valve replacement. Stepwise regression of the data demonstrated myocardial fibrosis and chronic arteriolopathy were remarkably correlated to the heart functions a Her the operation, especially myocardial fibrosis. Discriminants were obtained by stepwise discrimination analysis, and they may be used as predictors.