摘要
对乙型肝炎72例小儿患者肝组织标本,用免疫组织化学方法(ABC法)检测肝内HBsAg和HBcAg的显现情况,并与成人乙型肝炎101例患者肝组织的检验结果进行比较。结果显示,小儿乙肝时肝内HBsAg和HBcAg的显现与成人有所不同:(1)小儿肝HBcAg阳性率显著低于成人;(2)在阳性病例中,小儿肝内HBsAg或HBcAg阳性细胞数显著少于成人。这可能反映小儿HBV感染时,乙肝病毒抗原表达比成人少。
Expression of HBsAg and HBcAg in 72 samples of liver tissue from children with hepatitis B was determined with immunohistochemical technique (the ABC method) and compared with that of 101 samples of liver from adults. The results showed that the positive rate for HBcAg in children was significantly lower than that in adults; in the positive cases, the HBsAg or HBcAg positive cells in liver sections from child patients were fewer than in those from adults. The different expression patterns may reflect the different immunological responseness between children and adults.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
1991年第1期26-29,共4页
Medical Journal of Chinese People's Liberation Army
