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多标记联合检测对肺癌诊断的研究 被引量:2

MULTIPLE BIOMARKER ASSAY IN PATIENTS WITH LUNG CANCER
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摘要 观察肺癌患者99例,肺炎患者60例和对照者23名血清和支气管肺泡灌洗液的癌胚抗原、溶菌酶、铁蛋白和β_2-微球蛋白的浓度。比较了病侧与健侧浓度差别,探讨了单项肺癌标记物的诊断价值,提出了较好的判别式。联合检测血清和支气管肺泡灌洗液中多标记物有助于提高肺癌诊断的敏感性和特异性。 The levels of CEA, Lys, Fr and β2-MG of serum and brochoalveolar lavage fluid (BALF) were determined in 99 patients with inflammatory lung diseases and 23 healthy subjects for controls. Their levels in BALF were compared between diseased and normal sides of lungs. The value of diagnosis of individual formulas was suggested. The combined ditermination of multiple biomarkers in serum and BALF can help to raise the positivity and spcificity of diagnosis of lung cancer.
出处 《解放军医学杂志》 CAS CSCD 北大核心 1991年第5期350-353,共4页 Medical Journal of Chinese People's Liberation Army
关键词 肺肿瘤 多标记 检测 诊断 Lung cancer Bronchoalveolar lavage fluid Carcinoembryonic antigen Ferritin Lysozyme β2-Microglobulin
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