摘要
本研究用HRP逆行追踪和免疫细胞化学结合法,研究了大白鼠中脑导水管周围灰质(PAG)以及Edinger-Westphal(E-W)核至脊髓的SP能和CCK能神经投射。结果表明,PAG腹外侧区至脊髓颈、胸、腰段双侧均有少量投射,但以同侧为主。在这些下行投射神经元中,约有48%为SP样免疫反应阳性。E-W核至脊髓的颈、胸、腰段均有广泛投射,其中约有70%为SP样免疫反应阳性,73%为CCK样免疫反应阳性。提示至少有一部分E-W核的脊髓投射神经元含有SP和CCK两种神经递质。
Projections from substance P (SP)-and cholecystokinin (CCK) containing neurons in the periaqueductal gray(PAG)and Edinger-Westphal(E-W)nucleus to the spinal cord were studied by means of the combining method of HRP tracing with immunocytochemistry in rats. The results showed that a few neurons in the ventrolateral region of PAG projected bilaterally to the cervical, thoracic and lumbar segments of the spinal cord, with the predominant projections from the ipsilateral side. The authors reported that these descending projection neurons showed SP-like immunoreactivity for the first time(account for 48%). The neurons of E-W nucleus projected diffusely to all segments of the spinal cord contained SP (70%) or CCK (73%) respectively, suggesting that at least a part of E-W neurons projecting to the spinal cord contain both SP and CCK.
出处
《解剖学报》
CAS
CSCD
北大核心
1991年第1期25-30,共6页
Acta Anatomica Sinica
基金
中国科学院科学基金资助的课题
关键词
脑灰质
E-W核
脊髓
免疫细胞化学
Periaqueductal gray
Edinger-Westphal nucleus
Spinal cord
HRP tracing
Immunocytochemistry