不同胎龄手掌侧皮肤皮嵴的分化特征

DIFFERENTATION CHARACTERISTIC OF THE DERMAL RIDGES OF THE VOLAR SKIN IN THE FETUS AT THE DIFFRENT AGE

按常规石蜡包埋、连续切片,H—E染色和用3%KOH孵化除去表皮,然后用0.05%甲苯胺蓝染色两种方法,观察了胎龄10—22周胚胎手掌侧皮肤皮嵴分化、发育的形态学特征。(1) 12～14周。腺褶和乳头原基开始形成.(2) 14～16周,腺褶分化为汗腺原基,表皮开始角化。(3) 16～18周,沟褶发生,汗腺开始分化。(4)18～22周,真皮嵴明显,表皮嵴渐外显。

The differentation characteristic of the dermal ridges were divided into 4 stage: (1) At 12 to 14 weeks,the glandular fold and the dermal papillare were formed on the epidermais-corium border. (2) The sweat anlagen was differentated in I4 to 16 weeks. (3) From 16 to 18 weeks, the furrow fold was formed between the glandular fold.(4) After 18 week, the epidermal ridge appear gradually at the surface of the hand volar skin.