白细胞滤过血输注与胃肠道癌患者术后感染的关系

Relationship between transfusion of white cell filtering blood and postoperative infections in the patients with gastrointestinal carcinomas

目的 :探讨胃肠道癌患者术后感染与输血及血液成分的关系。方法 :回顾性分析了 2 81例胃肠道癌患者术后感染的多种因素。结果 :2 81例中有 117例进行了围手术期输血 ,其中 34例输白细胞滤过血 ,感染率为 5 9% ;83例输全血或压积红细胞 ,感染率为 36 1%。 16 4例未输血 ,术后感染率为 4 3 %。两两比较差异有显著性 (P <0 0 5 ) ,且术后感染发生率随输血量增加而增大。结论 :胃肠道癌患者术后感染的发生与输血、血液成分及输血量等有关。故在保证患者能够耐受手术的情况下 ,应尽量不输血或少输血 ,对确需输血的患者 ,应输白细胞滤过血 ,提高输血质量 。

Aim:To study the relationship between postoperative infections in the patients with gastrointestinal carcinomas and blood transfusion and its composition. Methods: Various factors of postoperative infections in 281 cases of gastrointestinal carcinomas were retrospectively analyzed. Results: A total of 117 cases underwent perioperative transfusion. The postoperative infection rate was 5.9% in 34 cases who were transfused white cell filtering blood and 36.1% in 83 cases who were transfused whole blood or packed red cell. And in 164 cases without perioperativel transfusion, the postoperative infection rate was only 4.3%. There were significant differences in the infection rates between the tranfusion groups and the controls ( P <0.05). The results demonstrated that postoperative infection rate increased with the amount of transfusion. Conclusions: The postoperative infection complications relate to transfusion, blood composition and the amount of transfusion. So if the patients can safely undergo an operation, transfusion should not be given or give as less as possible. If transfusion is needed for a patient, it is best to give white cell filtering blood and improve transfusion quanlity to prevent postoperative infection.