中药离子导入治疗肝硬化门静脉高压征的临床研究

Clinical Study on Hepatic Cirrhotic Portal Hypertension Treated with Iontophoresis of Chinese Drugs

目的：观察中药离子导入治疗肝硬化门静脉高压征的降压效果。方法：４６例门静脉高压征患者随机分成两组。治疗组（２６例）用中药离子导入治疗，用彩色多普勒观察治疗前后血流动力学变化；对照组（２０例）口服心得安。结果：治疗组门静脉和脾静脉内径分别缩小，总有效率分别为６１．５％、５３．６％，与对照组（２５．０％、２０，０％）比较，有显著差异（Ｐ＜０．０５）。中药离子导入治疗后门脉系统血流量明显减少。结论：中药离子导入治疗肝硬化有明显降低门静脉压的效果。

To explore the clinical effect of chinese herbal medicine in treating Hepatic Grrhotic Portal Hypertension (HCPH). Methods: The 46 cases of HCPH were divided into two groups randomly. The treatment group (26 cases) were with iontophoresis of Chinese herbal medicine once a day for 30 days. Hemadynamics changes before and after treatment were observed with colour Doppler. Another 20 cases were used as control group with take progranol orally. Results: The whole effective rate for decrease of diameter of Portal Vein(PV) and Spleen Vein ( SV) in the treatment group (61.5% , 53.6%) were higher than that in control group(25.0% ,20.0%)(p < 0.05).The portal vein system blood flow reduced significantly after iontophoresis of chinese herbal medicine. Conclusion: Iontophoresis of Chinese herbal medicine has marked effect on lowering portal hypertension.